The Cardiovascular Tissue Engineering laboratory works transversally on in silico, in vitro and in vitro models. The group deals with mechanical-structural characterization, biofabrication of bioengineered tissues, and the study of the growth of endogenous tissue with the aim of developing new medical devices and treatments for cardiovascular diseases.

Aims

• Development of advanced biofabrication methods for cardiac tissue engineering
• Development of bioinspired medical devices and tissue engineering strategies to address cardiovascular diseases
• Computational modelling for cardiovascular tissue engineering

Focus

• Tissue engineered heart valve
• Tissue engineered vascular graft
• Tissue engineered cardiac patch
• Bioreactors for Enhanced Extra Cellular Matrix elaboration
• Native/engineered tissue image-based structural and histopathological analysis
• Native/engineered tissue numerical models for mechanics and tissue growth

Expertise and resources

• Biofabrication of engineered tissue
• Biomaterial processing
• Mechanical and physical-chemical characterization of native and engineered tissue
• Qualitative and quantitative histological assessment
• Formulation and characterization of controlled drug-release medical devices
• Mechanobiology
• Numerical models applied to tissue growth/degradation and structural image-based analysis
• In vivo assessment of biomaterials and engineered tissue

Team