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Antonio-D'Amore-2
Antonio D'Amore, PhD
Group Leader in Tissue Engineering
adamore@fondazionerimed.com

Biographical notes

Prof. Antonio D’Amore is the group leader and head of the Tissue Engineering program at Ri.MED Foundation, he also serves as Assistant Professor in the Departments of Surgery and Bioengineering at the University of Pittsburgh. Prof. D’Amore received his MS in Mechanical Engineering from the University of Palermo (Italy) in 2004.  He continued his studies at the Imperial College of London, United Kingdom, obtaining in 2007 an MS in Biomedical Engineering.

In 2011, Prof. D’Amore earned his PhD in Biomechanics and Tissue Engineering from a joint program by the University of Palermo (Italy) and the University of Pittsburgh. Since 2008, Prof. D’Amore has been a bioengineering industry consultant in both the U.S. and Italy. He is the author of more than 170 publications, including peer-reviewed journal articles (>49), book chapters (2), international conference abstracts and extended abstracts (>110), biomedical devices patents applications (11), U.S. and EU-issued patents (5), and software to model biological systems (2). The value of this intellectual property has been recognized by several professional societies, translational science, and career awards such as the National Academy of Inventors (senior member), the “Strazzabosco’s” award for young engineers granted under the patronage of the Italian president of the Republic, or the Coulter’s Foundation Translational Research award. He has been the recipient of numerous research awards, he obtained as PI or Co-I, which cumulatively secured funding for more than $10.2 M. Prof. D’Amore is the co-founder and Chief Technology Officer of “Neoolife” the first RiMED- Pitt startup focusing on tissue engineering heart valve technology.

Scientifical activity

Prof. D’Amore’s mission as Ri.MED group leader is to establish a successful cardiovascular tissue engineering program. The D’Amore’s lab, now 22 people strong, seeks to couple a mechanistic understanding of the relationship between scaffolds micro-structure, mechanics, and endogenous tissue growth with the development of novel biomaterials for tissue engineering strategies.

The focus of D’Amore’s lab research is upon unmet clinical needs in cardiovascular diseases. Recent areas of interest include: quantitative histology and biomaterials micro-structure image-based analysis, structural modeling strategies to guide tissue engineering scaffold fabrication, mechanical and topological conditioning for tissue elaboration, development of cardiac restrain devices, vascular grafts and engineered heart valves. Prof. D’Amore’s project funding comes from the National Institutes of Health, European Research Council (ERC-CoG BIOMITRAL with host RiMED Italy), RiMED Foundation, The Wallace H. Coulter Foundation, and the University of Pittsburgh.

Publications

Journal Paper
Mammary tissue-derived extracellular matrix hydrogels reveal the role of irradiation in driving a pro-tumor and immunosuppressive microenvironment
Tian Zhu , Steven M Alves , Arianna Adamo, PhD , Xiaona Wen , Kevin C Corn , Anastasia Shostak , Shereena Johnson , Nicholas D Shaub , Shannon E Martello , Benjamin C Hacker , Antonio D'Amore, Ph.D. , Rizia Bardhan , Marjan Rafat
https://doi.org/10.1016/j.biomaterials.2024.122531
Dissemination
Comparative Assessment of Prosthetic Biomaterials for Cardiac Applications
Danila Vella, PhD †, Parnaz Boodagh †, Laura Modica De Mohac, PhD , Sang-Ho Ye , Federica Cosentino, PhD , Federica Scaglione , William Wagner , Antonio D'Amore, Ph.D. , Gaetano Burriesci, PhD
Proceedings of the 9th World Congress on Electrical Engineering and Computer Systems and Sciences (EECSS’23), ICBES 137, 2023. DOI: 10.11159/icbes23.137
https://avestia.com/EECSS2023_Proceedings/files/paper/ICBES/ICBES_137.pdf
Journal Paper
Continuous Microfiber Wire Mandrel-Less Biofabrication for Soft Tissue Engineering Applications
Arianna Adamo, PhD , Joseph G. Bartolacci , Drake D. Pedersen , Marco G. Traina , Seungil Kim , Antonio Pantano , Giulio Ghersi , Simon C. Watkins , William R. Wagner , Stephen F. Badylak , Antonio D'Amore, Ph.D.
https://doi.org/10.1002/adhm.202270075
Journal Paper
Adipose-derived stem cell sheet under an elastic patch improves cardiac function in rats after myocardial infarction
Noriyuki Kashiyama , Robert L. Kormos , Yasumoto Matsumura , Antonio D'Amore, Ph.D. , Shigeru Miyagawa , Yoshiki Sawa , William R. Wagner
https://doi.org/10.1016/j.jtcvs.2020.04.150
Journal Paper
Can a Biohybrid Patch Salvage Ventricular Function at a Late Time Point in the Post-Infarction Remodeling Process?
Lindemberg M Silveira-Filho , Garrett N Coyan , Arianna Adamo , Samuel K Luketich , Giorgio Menallo , Antonio D'Amore, Ph.D. , William R Wagner
https://10.1016/j.jacbts.2021.01.004
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