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Laura-Modica-De-Mohac
Laura Modica de Mohac, PhD
Post Doctoral Researcher - Expert in Bioprocessing
lmodicademohac@fondazionerimed.com

Biographical notes

Dr. Laura Modica de Mohac is a Postdoctoral Research Fellow at the RiMED Foundation and a pharmacist. After earning her bachelor’s degree in Pharmacy and Industrial Pharmacy (2016), Laura completed a Ph.D. through a joint program between the University of Palermo and King’s College London, where she developed devices for the controlled release of medications for treatment-resistant schizophrenia (2021).

During her work as a Teaching Fellow in Pharmacy, Pharmaceutical Sciences, and Biopharmaceutics, she was recognized as an Associate Fellow by the Higher Education Academy at King’s College London (2020).

Scientific activity

Dr. Laura’s project focuses on a biofabrication process to develop a multi-layered bio-hybrid cardiac patch to improve cardiac function and reduce maladaptive remodeling following acute myocardial infarction. In her role, she collaborates with a team of clinicians and engineers to produce a new class of engineered medical devices for both cardiovascular and gastrointestinal applications. Specifically, she is involved in the development of multi-layered bio-hybrid tubular structures such as vascular and esophageal grafts, and is working on the creation of a TIPS (Transjugular Intrahepatic Portosystemic Shunt) for the treatment of portal hypertension.

She is currently collaborating on two international projects involving countries such as the United States and Argentina, and is pursuing two collaborations with the University of Palermo and the University of Cagliari.

Her main areas of expertise include: the chemical-physical characterization of solid materials (differential scanning calorimetry, Fourier transform spectroscopy), decellularization protocols (whole heart, heart valves, and small intestinal submucosa), biofabrication techniques (electrospinning, TIPS), polymer synthesis, and image and data analysis (Scanning Electron Microscopy SEM, optical microscopy, MatLab).

Publications

Journal Paper
Photo-oxidation crosslinked, glutaraldehyde crosslinked, or enzyme and hydrostatic pressure processed decellularized biomaterials for cardiovascular repair do not affect host response in a rat right ventricular outflow flow tract reconstruction (RVOT) model
Parnaz Boodagh †, Laura Modica De Mohac, PhD , Yasurani Hayashi , Danila Vella, PhD , Sang-Ho Ye , Federica Cosentino, PhD , Taro Fujii , Emily Gorge , Garrett Coyan , Laubrie Soto Joan Dario, PhD , Gaetano Burriesci, PhD , William R Wagner , Antonio D'Amore, Ph.D.
Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 113(2):e35529, 2025.
https://doi.org/10.1002/jbm.b.35529
Journal Paper
In Vitro Evaluation of Biomaterials for Heart Valve Prosthesis: High Hydrostatic and Enzymatic Treatments as Alternative for Bio-Derived Materials
Danila Vella, PhD †, Parnaz Boodagh , Laura Modica De Mohac, PhD , Sang-Ho Ye , Federica Cosentino, PhD , Federica Scaglione , Sofia Dei Bardi , Giulia Polizzi , Garrett Coyan , William R. Wagner , Gaetano Burriesci, PhD , Antonio D'Amore, Ph.D. *
Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 113(6): e35592, 2025.
https://doi.org/10.1002/jbm.b.35592
Dissemination
Comparative Assessment of Prosthetic Biomaterials for Cardiac Applications
Danila Vella, PhD †, Parnaz Boodagh †, Laura Modica De Mohac, PhD , Sang-Ho Ye , Federica Cosentino, PhD , Federica Scaglione , William Wagner , Antonio D'Amore, Ph.D. , Gaetano Burriesci, PhD
Proceedings of the 9th World Congress on Electrical Engineering and Computer Systems and Sciences (EECSS’23), ICBES 137, 2023. DOI: 10.11159/icbes23.137
https://avestia.com/EECSS2023_Proceedings/files/paper/ICBES/ICBES_137.pdf
Journal Paper
Photo-oxidation crosslinked, glutaraldehyde crosslinked, or enzyme and hydrostatic pressure processed decellularized biomaterials for cardiovascular repair do not affect host response in a rat right ventricular outflow flow tract reconstruction (RVOT) model
Parnaz Boodagh †, Laura Modica De Mohac, PhD , Yasurani Hayashi , Danila Vella, PhD , Sang-Ho Ye , Federica Cosentino, PhD , Taro Fujii , Emily Gorge , Garrett Coyan , Laubrie Soto Joan Dario, PhD , Gaetano Burriesci, PhD , William R. Wagner , Antonio D'Amore, Ph.D. *
Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 113(2):e35529 (2025)
https://doi.org/10.1002/jbm.b.35529
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