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Research founding

The Ri.MED Foundation supports the realization of its scientific activity through funding opportunities offered by public and private bodies, regional, national and international institutions. Accessing research funds is a strategic activity for the Foundation.

For this reason, a Grants Office was established to select financial programs supporting biomedical research, specialized training and international cooperation, submitting proposals (also in collaboration with other bodies) and managing relationships with administrations managing financing programs, as well as coordinating and supervising the approved projects.

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Ricerca grants
Filtro grants

Benign and malignant esophageal stricture, an innovative approach to address an unmet clinical need: a biohybrid polymer – extracellular matrix, drug-eluting, esophageal prosthesis able to provide sustained mechanical support, actively prevent re-stenosis and induce constructive tissue remodeling

Progetto in Corso
Italian Ministry of Health - National Recovery and Resilience Plan (NRRP) - Mission 6 - Component 2 - Investment 2.1. Strengthening and enhancing biomedical research in the NHS_CALL 2023. Objective: validating a medical device that can address clinical deficiencies in a non-pathological model, allowing for the assessment of the local mechanical, immunological, and histological effects of the esophageal graft under study.

Early Drug Discovery to identify novel inhibitors of Prenylcysteine oxidase 1 (PCYOX1), a novel target in cardiology and oncology

Progetto in Corso
Italian Ministry of Health - National Recovery and Resilience Plan (NRRP) - Mission 6 - Component 2 - Investment 2.1. Strengthening and enhancing biomedical research in the NHS_CALL 2023 Objective: to validate the druggability of PCYOX1 and identify potential hit compounds directed against it for the future development of cardiovascular and anticancer drugs.

BioChord: biomimetic engineered chordae tendineae for valve repair and regeneration

Progetto in Corso
European Research Council (ERC) - Proof Of Concept (ERC-2023-POC) Objective: to develop better Mitral Valve repair techniques that are simple, effective, and durable, further advancing and validating BioChord, the first ever polymeric bioengineered regenerative Chordae Tendinae, designed to first repair the MV by replacing the diseased CT.

SMART4SCLERO – Smart Injectable Scaffolds for Sclerostin Based Bone Resorption Treatment

Progetto in Corso
Ministry of University and Research – PRIN Call 2022 (Progetti di Ricerca di Rilevante Interesse Nazionale/ Research Projects of Relevant National Interest) on behalf of the project Coordinator Consiglio Nazionale delle Ricerche (Napoli). Objective: developing an advanced in vitro model of joints’ disorders dependent from bowel-related pathologies. The model will be based either on native than engineered tissues cultured in static, and dynamic conditions. These latter will be fabricated using the support of the bioprinting, as well as other additive manufacturing technologies.

Complex graphical models for biological network science

Progetto in Corso
Ministry of University and Research – PRIN Call 2022 (Progetti di Ricerca di Rilevante Interesse Nazionale/ Research Projects of Relevant National Interest) on behalf of the project Coordinator Università degli Studi di Firenze. Objective: collection and pre-processing of omics data and interpretation of results obtained by the novel statistical models developed within the project.

Exploiting the power of human induced pluripotent stem cell extracellular vesicles

Progetto in Corso
National Recovery and Resilience Plan (NRRP) – Mission 6 (Health), Component 2 – Investment 2.1. Enhancement and strengthening of NHS biomedical research. (Proof Of Concept). Objective: to assess the technical and commercial feasibility of an innovative cell-free nanomedicine strategy based on extracellular vesicles (EV), human induced pluripotent stem cells, and a young cell source.

Translating protection of cell-surface receptor LRP1 into potential disease-modifying therapies for osteoarthritis

Progetto in Corso
Versus Arthritis - Bridging fellowship 2023, on behalf of the project Coordinator University of Liverpool (United Kingdom). Objective: using high-resolution proteomics to identify binding partners of the low-density-liporptoein receptor related protein 1 (LRP-1) in osteoarthritic cartilage. In brief, proteins will be purified from osteoarthritic and normal cartilage, and then applied to an agarose resin coupled with LRP-1 previously purified from placenta. Proteins binding to LRP-1 will be eluted, digested by FASP and analysed by LC-MS/MS. 

Life Science TTO Network

Progetto in Corso
Italian Ministry of Health. National Plan for complementary investments to the NRRP – “Innovative Health Ecosystem” Program – Investment E.3. Objective: establishing and consolidating a nationwide open and sustainable Technology Transfer Office (TTO) Network, to make available world-class services in a synergistic valuable way at national and international level in the health sector.

National Center for Gene Therapy and Drugs based on RNA Technology

Progetto in Corso
National Recovery and Resilience Plan (NRRP) - Mission 4 Component 2 Investment 1.4 funded from the European Union - NextGenerationEU. Objective: to increase the technological know-how needed to design and deliver RNA-based and gene therapy medicines and identify promising drug/gene candidates in five human disease areas (genetic diseases, cancer, metabolic/cardiovascular diseases, neurodegenerative diseases and inflammatory/ infectious).
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