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Research founding

The Ri.MED Foundation supports the realization of its scientific activity through funding opportunities offered by public and private bodies, regional, national and international institutions. Accessing research funds is a strategic activity for the Foundation.

For this reason, a Grants Office was established to select financial programs supporting biomedical research, specialized training and international cooperation, submitting proposals (also in collaboration with other bodies) and managing relationships with administrations managing financing programs, as well as coordinating and supervising the approved projects.

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Ricerca grants
Filtro grants

Translating protection of cell-surface receptor LRP1 into potential disease-modifying therapies for osteoarthritis

Progetto in Corso
Versus Arthritis - Bridging fellowship 2023, on behalf of the project Coordinator University of Liverpool (United Kingdom). Objective: using high-resolution proteomics to identify binding partners of the low-density-liporptoein receptor related protein 1 (LRP-1) in osteoarthritic cartilage. In brief, proteins will be purified from osteoarthritic and normal cartilage, and then applied to an agarose resin coupled with LRP-1 previously purified from placenta. Proteins binding to LRP-1 will be eluted, digested by FASP and analysed by LC-MS/MS. 

The addition of simvastatin portal venous infusion to cold storage solution of explanted whole liver grafts for facing ischemia/reperfusion injury in an area with low rate of deceased donation

Progetto Concluso
Founded by: Italian Ministry of Health within the scope of the 2013 Finalized Research Program. The goal of the project is to test the clinical efficacy of simvastatin administration by gavage three hours prior to whole liver cross-clamp in the deceased donor. This monocentric, prospective, randomized, double-blind study provides for the enrollment of 106 patients and comparison with standard procedure on placebo sample.

SMART4SCLERO – Smart Injectable Scaffolds for Sclerostin Based Bone Resorption Treatment

Progetto in Corso
Ministry of University and Research – PRIN Call 2022 (Progetti di Ricerca di Rilevante Interesse Nazionale/ Research Projects of Relevant National Interest) on behalf of the project Coordinator Consiglio Nazionale delle Ricerche (Napoli). Objective: developing an advanced in vitro model of joints’ disorders dependent from bowel-related pathologies. The model will be based either on native than engineered tissues cultured in static, and dynamic conditions. These latter will be fabricated using the support of the bioprinting, as well as other additive manufacturing technologies.

SE.N.SO. – SEnsore Nanostrutturato per Stress Ossidativo (Development of a miniaturized device for monitoring oxidative stress in cellular systems)

Progetto Concluso
Sicilian Region - OP ERDF 2014/2020 Action 1.1.5 Objective: creating a nanosensor to detect hydrogen peroxide (H2O2) released in vitro/ex vivo cellular system culture. The project aims at making available an innovative, robust, reliable, and small-sized lab tool to monitor the H2O2 release within the culture in real time, without affecting the cells' growth conditions.

PROMETEO – Prodotti medicinali derivati da placenta per terapie avanzate per patologie epatiche ed endometriali

Progetto Concluso
Sicilian Region - OP ERDF 2014/2020 Action 1.1.5 Objective: to develop cell-based products from stem cells isolated from the placenta for clinical applications. Through in vitro and in vivo studies, cellular therapies will be developed to treat acute and chronic liver diseases and reactivate the endometrium. The therapeutic effects of cells and by-products will be tested on in vivo models of acute and chronic liver injury and on in vitro models for endometrial reactivation. All tasks will be optimized according to the principles of Good Manufacturing Practices (GMP) to develop cellular therapies.

OACTIVE – Advanced personalised, multi-scale computer models preventing OsteoArthritis

Progetto Concluso
Founded by: HORIZON 2020 Action SC1-PM-17 European Commission The goal of the project is to develop models to improve osteoarthritis diagnosis and treatment using a holistic approach, providing for the integration of patient-specific information from different sources (cells, tissues, organs) with behavioral patterns and socio-environmental risk factors.
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