Research founding
The Ri.MED Foundation supports the realization of its scientific activity through funding opportunities offered by public and private bodies, regional, national and international institutions. Accessing research funds is a strategic activity for the Foundation.
For this reason, a Grants Office was established to select financial programs supporting biomedical research, specialized training and international cooperation, submitting proposals (also in collaboration with other bodies) and managing relationships with administrations managing financing programs, as well as coordinating and supervising the approved projects.
Search for a project or filter it based on available options
Translating protection of cell-surface receptor LRP1 into potential disease-modifying therapies for osteoarthritis
Progetto in Corso
Versus Arthritis - Bridging fellowship 2023, on behalf of the project Coordinator University of Liverpool (United Kingdom).
Objective: using high-resolution proteomics to identify binding partners of the low-density-liporptoein receptor related protein 1 (LRP-1) in osteoarthritic cartilage. In brief, proteins will be purified from osteoarthritic and normal cartilage, and then applied to an agarose resin coupled with LRP-1 previously purified from placenta. Proteins binding to LRP-1 will be eluted, digested by FASP and analysed by LC-MS/MS.
The addition of simvastatin portal venous infusion to cold storage solution of explanted whole liver grafts for facing ischemia/reperfusion injury in an area with low rate of deceased donation
Progetto Concluso
Founded by: Italian Ministry of Health within the scope of the 2013 Finalized Research Program.
The goal of the project is to test the clinical efficacy of simvastatin administration by gavage three hours prior to whole liver cross-clamp in the deceased donor. This monocentric, prospective, randomized, double-blind study provides for the enrollment of 106 patients and comparison with standard procedure on placebo sample.
SMART4SCLERO – Smart Injectable Scaffolds for Sclerostin Based Bone Resorption Treatment
Progetto in Corso
Ministry of University and Research – PRIN Call 2022 (Progetti di Ricerca di Rilevante Interesse Nazionale/ Research Projects of Relevant National Interest) on behalf of the project Coordinator Consiglio Nazionale delle Ricerche (Napoli).
Objective: developing an advanced in vitro model of joints’ disorders dependent from bowel-related pathologies. The model will be based either on native than engineered tissues cultured in static, and dynamic conditions. These latter will be fabricated using the support of the bioprinting, as well as other additive manufacturing technologies.
SE.N.SO. – SEnsore Nanostrutturato per Stress Ossidativo (Development of a miniaturized device for monitoring oxidative stress in cellular systems)
Progetto Concluso
Sicilian Region - OP ERDF 2014/2020 Action 1.1.5
Objective: creating a nanosensor to detect hydrogen peroxide (H2O2) released in vitro/ex vivo cellular system culture. The project aims at making available an innovative, robust, reliable, and small-sized lab tool to monitor the H2O2 release within the culture in real time, without affecting the cells' growth conditions.
PROMETEO – Prodotti medicinali derivati da placenta per terapie avanzate per patologie epatiche ed endometriali
Progetto Concluso
Sicilian Region - OP ERDF 2014/2020 Action 1.1.5
Objective: to develop cell-based products from stem cells isolated from the placenta for clinical applications. Through in vitro and in vivo studies, cellular therapies will be developed to treat acute and chronic liver diseases and reactivate the endometrium. The therapeutic effects of cells and by-products will be tested on in vivo models of acute and chronic liver injury and on in vitro models for endometrial reactivation. All tasks will be optimized according to the principles of Good Manufacturing Practices (GMP) to develop cellular therapies.
PROGEMA – Processi green per l’estrazione di principi attivi e la depurazione di matrici di scarto e non
Progetto Concluso
Italian Ministry of Education, University and Research, NOP Research and Innovation 2014-2020
Objective: to improve the treatment of vegetation waters of the oil production chain to extract and reallocate pharmacologically active organic compounds, reduce their polluting effect, and reuse treated waters in the production processes.
Piano delle attività “TRASFERIMENTI PER METODOLOGIE INNOVATIVE NEL CAMPO DELLE BIOTECNOLOGIE 2018″
Progetto Concluso
Legge di stabilità Regione Siciliana Assessorato Salute Dipartimento DASOE
Obiettivo: sostenere e potenziare le attività di ricerca del cluster Ri.MED-ISMETT nei settori della medicina rigenerativa, immunoterapia, bio-ingegneria e medicina di precisione
OBIND – Oncological therapies through Biological Interaction Network Discovery
Progetto Concluso
Sicilian Region - OP ERDF 2014/2020 Action 1.1.5
Objective: to study the biological interactions influencing tumor diseases using new statistical and computational data processing methods, and multiple source integrated data analysis model application.
OACTIVE – Advanced personalised, multi-scale computer models preventing OsteoArthritis
Progetto Concluso
Founded by: HORIZON 2020 Action SC1-PM-17 European Commission
The goal of the project is to develop models to improve osteoarthritis diagnosis and treatment using a holistic approach, providing for the integration of patient-specific information from different sources (cells, tissues, organs) with behavioral patterns and socio-environmental risk factors.