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Viale delle Scienze, Ed. 18
90128 Palermo, ITALY
bioengineering@fondazionerimed.com

Bioengineering Platform

Academic Collaborations:

  • ISMETT- IRCCS, Palermo, IT
  • Policlinico Giaccone, Palermo, IT
  • Università degli Studi di Palermo, IT
  • Institute Foundation G. Giglio, IT
  • Università degli studi di Padova, IT
  • Université de Technologie de Compiègne, FR
  • Barts Heart Centre at St Bartholomew’s Hospital, GB
  • Great Ormond Street Hospital for Children, GB
  • University College London, GB
  • Queen Mary University of London, GB
  • University of Bristol, GB
  • University of Leeds, GB
  • University of Pittsburgh, US
  • University of Alabama at Birmingham, US
  • Adeka, JP

Description

The Bioengineering group applies engineering principles and physical science to the analysis of biological systems and the development of advanced diagnostic solutions, support tools for therapeutic planning and new generation medical devices.

Our research team offers solid skills in the numerical modelling of fluid-structural biomechanical problems, the design optimisation of medical devices and in the conduction of preclinical validations, based on regulatory requirements and good practice.

In collaboration with clinical and industrial partners, we support and facilitate the introduction of novel therapeutic solutions into clinical practice to maximise their positive impact on patients’ quality of life.

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Team

Anna Maria Lo Presti

PhD Student in Chemical, Environmental, Biomedical, Hydraulic And Materials Engineering - University of Palermo

  • FORMER MEMBERS

    • Federica Scaglione – Holder of a 1-year Scholarship (2022-23) in Bioengineering (Ref. Innova-Bioing/21) to perfect her technical-scientific skills on the topics of the characterisation of biomaterials and cardiovascular medical devices, and for the in vitro simulation of physiological systems computational and experimental Bioengineering.
  • INTERNS AND STUDENTS

    Students and interns that support and have supported our research activities:

    2023

    • Salvatore Tornabene, “Validazione sperimentale e computazionale di un Organ-on-Chip per la stimolazione meccanica di colture cellulari (Experimental and computational validation of an Organ-on-Chip for the mechanical stimulation of cell cultures)”, University of Palermo, Italy
    • Alessandro Parrinello, “Analisi dell’influenza del sistema di ancoraggio nella caratterizzazione di tessuti biologici mediante test biassiali (Analysis of the influence of the anchoring system in the characterisation of biological tissues using biaxial tests)”, University of Palermo, Italy
    • Dario Calò, “Simulazione numerica dell’inserimento di un allineatore nell’arcata dentale inferiore (Numerical simulation of the insertion of an aligner in the lower dental arch)”, ITS Alessandro Volta, Palermo, Italy
    • Valentina Di Miceli, “Caratterizzazione meccanica mediante Digital Image Correlation di leghe di Ni-Ti per dispositivi biomedicali (Mechanical characterisation of Ni-Ti alloys for biomedical devices by means of Digital Image Correlation)”, University of Palermo, Italy
    • Arianna Di Piazza “Studio sperimentale e numerico delle alterazioni nel flusso aortico introdotte dalla superficie corrugata di graft sostitutivi (Experimental and numerical study of the alterations in aortic flow introduced by the corrugated surface of replacement grafts)”, University of Palermo, Italy
    • Federica Armetta “Impiego di tecniche di Digital Image Correlation per la valutazione di tensioni residue su tessuti sintetici e biologici (Use of Digital Image Correlation techniques for the evaluation of residual stresses on polymeric membranes and biological tissues)”, University of Palermo, Italy
    • Bernadette Bondì, “Analisi numerica dei flussi ematici nelle cannule per perfusione (Numerical analysis of blood flows in perfusion cannulae)”, University of Palermo, Italy

    2022

    • Angela Franco, “Modellazione numerica della trombosi in aneurismi cerebrali con il metodo SPH (Numerical modelling of thrombosis in cerebral aneurysms with the SPH method)”, University of Palermo, Italy
    • Valentina Caldarella, “Modelli in-vitro di calcificazione e degenerazione di biomateriali e tessuti di origine biologica, utilizzati nelle protesi cardiovascolari (Calcification and degenerative in-vitro models for biomaterials and biological tissues, used in cardiovascular prostheses)”, University of Palermo, Italy

    2021

    • Patrizia Caruso “Tecniche sperimentali per la caratterizzazione meccanica di tessuti biologici in presenza di carichi biassiali (Experimental techniques for the mechanical characterisation of biological soft tissues subjected to biaxial loads)”, University of Palermo, Italy (now PhD Student in the Tissue Engineering Group)
    • Ruggero Cannova “Previsione del rischio trombo-embolico su modelli patient-specific di auricola atriale (Thrombo-embolic risk prediction on patient-specific atrial appendage models)”, University of Palermo, Italy
    • Valentina Pinto “Applicazioni di Particle Image Velocimetry in ambito cardiovascolare (Applications of Particle Image Velocimetry in the cardiovascular field)”, University of Palermo, Italy (now PhD Student in our Team)

Publications

Journal Paper
On preserving anatomical detail in statistical shape analysis for clustering: focus on left atrial appendage morphology
Matthew T. Lee †, Vincenzo Martorana , Rafizul Islam Md , Raphael Sivera , Andrew C. Cook , Leon Menezes , Gaetano Burriesci, PhD , Ryo Torii , Giorgia M. Bosi *

Frontiers in Network Physiology, 4:1467180, 2024.

https://doi.org/10.3389/fnetp.2024.1467180
Dissemination
Mitral Regurgitation And Atrial Fibrillation: An Explorative FluidStructure Interaction Study
Giulio Musotto, PhD †, Alessandra Monteleone, PhD †, Danila Vella, PhD , Leon Menezes , Andrew Cook , Giorgia M Bosi , Gaetano Burriesci, PhD *
Proceedings of the World Congress on New Technologies. 10th World Congress on New Technologies, NewTech 2024, Barcelona, 25-27 August 2024: 319749, 2024
http://dx.doi.org/10.11159/icbb24.123
Dissemination
Temperature Harmonic Analysis Of Austenitic Niti Under Dynamic Cyclic Loading
Valentina Pinto †, Sofia Di Leonardo, PhD , Maria Galeazzo , Gaetano Burriesci, PhD , Giuseppe Pitarresi
Proceedings of the World Congress on New Technologies. 10th World Congress on New Technologies, NewTech 2024, Barcelona 25-27 August: 319749, 2024
http://dx.doi.org/10.11159/icbb24.112
Dissemination
Comparative Assessment of Prosthetic Biomaterials for Cardiac Applications
Danila Vella, PhD †, Parnaz Boodagh †, Laura Modica De Mohac, PhD , Sang-Ho Ye , Federica Cosentino, PhD , Federica Scaglione , William Wagner , Antonio D'Amore, Ph.D. , Gaetano Burriesci, PhD
Proceedings of the 9th World Congress on Electrical Engineering and Computer Systems and Sciences (EECSS’23), ICBES 137, 2023. DOI: 10.11159/icbes23.137
https://avestia.com/EECSS2023_Proceedings/files/paper/ICBES/ICBES_137.pdf
Journal Paper
Valvulogenesis of a living, innervated pulmonary root induced by an acellular scaffold
Magdi H. Yacoub ‡, Yuan-Tsan Tseng , Jolanda Kluin , Annemijn Vis , Ulrich Stock , Hassiba Smail , Padmini Sarathchandra , Elena Aikawa , Hussam El-Nashar , Adrian H. Chester , Nairouz Shehata , Mohamed Nagy , Amr El-sawy , Wei Li , Gaetano Burriesci, PhD , Jacob Salmonsmith , Soha Romeih , Najma Latif
Communications Biology, 6 (1): 1017, 2023.
https://doi.org/10.1038/s42003-023-05383-z
Journal Paper
Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential
Claudio Procaccini , Silvia Garavelli , Fortunata Carbone , Dario Di Silvestre , Claudia La Rocca , Dario Greco , Alessandra Colamatteo , Maria Teresa Lepore , Claudia Russo , Giusy De Rosa , Deriggio Faicchia , Francesco Prattichizzo , Sarah Grossi , Paola Campomenosi , Fabio Buttari , Pierluigi Mauri , Antonio Uccelli , Marco Salvetti , Vincenzo Brescia Morra , Danila Vella, PhD , Mario Galgani , Maria Mottola , Bruno Zuccarelli , Roberta Lanzillo , Giorgia Teresa Maniscalco , Diego Centonze , Paola de Candia , Giuseppe Matarese
Immunity, 54(7): 1543-1560.e6, 2021
https://doi.org/10.1016/j.immuni.2021.04.014
Journal Paper
Incidence, predictors and cerebrovascular consequences of leaflet thrombosis (LT) after transcatheter aortic valve implantation (TAVI): a systematic review and meta-analysis
Fabrizio D’Ascenzo *, Stefano Salizzoni †, Andrea Saglietto †, Martina Cortese , Azeem Latib , Anna Franzone , Marco Barbanti , Fabian Nietlispach , Erik W Holy , Gaetano Burriesci, PhD , Alessandro De Paoli , Paolo Fonio , Paolo Fonio , Claudio Moretti , Leor Perl , Maurizio D’Amico , Mauro Rinaldi , Federico Conrotto
European Journal of Cardio-Thoracic Surgery, 56(3): 488-494, 2019.
https://doi.org/10.1093/ejcts/ezz099
Journal Paper
Low cost fabrication of PVA based personalized vascular phantoms for in vitro haemodynamic studies: three applications
Giacomo Annio †, Gaia Franzetti , Mirko Bonfanti , Antonio Gallarello , Andrea Palombi , Elena De Momi , Shervanthi Homer-Vanniasinkam , Helge A. Wurdemann , Victor Tsang , Vanessa Diáz-Zuccarini , Ryo Torii , Stavroula Balabani , Gaetano Burriesci, PhD *
ASME Journal of Engineering and Science in Medical Diagnostics and Therapy 2020, 3(3): 034501
https://doi.org/10.1115/1.4045760
Journal Paper
Anatomically realistic ultrasound phantoms using gel wax with 3D printed moulds
Efthymios Maneas , Wenfeng Xia , Daniil I Nikitichev , Batol Daher , Maniragav Manimaran , Rui Yen J Wong , Chia-Wei Chang , Benyamin Rahmani , Claudio Capelli , Silvia Schievano , Gaetano Burriesci, PhD , Sebastien Ourselin , Anna L David , Malcolm C Finlay , Simeon J West , Tom Vercauteren , Adrien E Desjardins
Physics in Medicine and Biology, 63(1): 015033, 2018.
https://iopscience.iop.org/article/10.1088/1361-6560/aa9e2c
Articolo di rivista
Pledget-armed sutures affect the hemodynamic performance of biologic aortic valve substitutes: a preliminary experimental and computational study
Claudio Capelli †, Chiara Corsini , Dario Biscarini , Francesco Ruffini , Francesco Migliavacca , Alfred Kocher , Guenther Laufer , Andrew M. Taylor , Silvia Schievano , Martin Andreas , Gaetano Burriesci, PhD , Claus Rath
Cardiovascular Engineering and Technology, 8(1): 17-29, 2017.
https://doi.org/10.1007/s13239-016-0284-8
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