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Exploiting the power of human induced pluripotent stem cell extracellular vesicles

Start/end date: May 2023 – June 2025

Funding Agency/Programme: Ministry of Health, National Recovery and Resilience Plan (NRRP)Mission 6 (Health), Component 2 – Investment 2.1. Enhancement and strengthening of NHS biomedical research. (Proof Of Concept).

Partnership:  Fondazione Cá Granda – Ospedale Maggiore Policlinico (Applicant); Fondazione Ri.MED (Partner); ISMETT IRCCS (Partner).

Abstract: The project aims to assess the technical and commercial feasibility of an innovative cell-free nanomedicine strategy based on extracellular vesicles (EV), human induced pluripotent stem cells, and a young cell source such as cord blood for the treatment of lung ischemia reperfusion injury. The project is focused on a patent which highlights the strong anti-inflammatory role of EV isolated from cord blood mesenchymal stromal induced pluripotent stem cells.

Ri.MED U.O.: Ingegneria del Tessuto Cardiovascolare
Ri.MED Principal InvestigatorAntonio D’Amore
Ri.MED Leading ScientistFederica Cosentino

 

Il progetto è finanziato dall’Unione Europea (NextGeneration EU), Missione 6/ Componente C2, Investimento: 2.1 Valorizzazione e potenziamento della ricerca biomedica del SSN

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